Jin Young Lee Selected Research

Lysine-tRNA Ligase

6/2021	Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis.
8/2014	Characterization of the interaction between lysyl-tRNA synthetase and laminin receptor by NMR.
1/2014	Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction.
10/2012	Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jin Young Lee Research Topics

Disease

21	Neoplasms (Cancer) 11/2021 - 03/2011
15	Pain (Aches) 03/2022 - 05/2009
8	Inflammation (Inflammations) 01/2021 - 12/2007
7	Neoplasm Metastasis (Metastasis) 06/2021 - 10/2010
7	Glaucoma 12/2016 - 12/2012
6	Colitis 01/2020 - 09/2005
5	Sarcopenia 01/2022 - 09/2020
5	Sepsis (Septicemia) 10/2021 - 01/2018
5	Wounds and Injuries (Trauma) 07/2021 - 10/2016
5	Pancreatic Neoplasms (Pancreatic Cancer) 04/2016 - 10/2010
4	Hyperalgesia 03/2022 - 07/2010
4	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 10/2021 - 12/2016
4	Neuralgia (Stump Neuralgia) 01/2021 - 07/2010
4	Infections 12/2020 - 12/2007
3	Cough 01/2022 - 05/2015
3	Flatulence 01/2021 - 12/2016
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 12/2016
2	Intracranial Hypotension 04/2022 - 12/2018
2	Bone Resorption 01/2022 - 11/2019
2	Dizziness (Lightheadedness) 01/2021 - 12/2016
2	Postoperative Pain 01/2021 - 01/2016
2	Headache (Headaches) 01/2021 - 12/2016
2	Body Weight (Weight, Body) 01/2021 - 05/2003
2	Critical Illness (Critically Ill) 01/2021 - 12/2018
2	Abdominal Pain (Pain, Abdominal) 12/2020 - 05/2019
2	Frailty 11/2020 - 10/2020
2	Failed Back Surgery Syndrome 09/2020 - 11/2013
2	Hemorrhage 09/2019 - 01/2013
2	Stroke (Strokes) 07/2019 - 10/2015
2	Atopic Dermatitis (Atopic Eczema) 01/2019 - 01/2017
2	Eosinophilia 09/2015 - 04/2006
2	Carcinogenesis 11/2013 - 03/2011
2	Enteritis 12/2007 - 09/2005
1	Osteoporosis 01/2022
1	Abdominal Injuries 12/2021
1	Ventilator-Associated Pneumonia 12/2021
1	Chronic Kidney Failure (Chronic Renal Failure) 12/2021

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 10/2021 - 06/2006
9	Retinaldehyde (Retinal)IBA 01/2018 - 12/2012
7	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2005
6	EnzymesIBA 01/2021 - 05/2003
5	Analgesics (Analgesic Drugs)IBA 01/2021 - 07/2010
5	SteroidsIBA 12/2020 - 11/2013
4	Lysine-tRNA LigaseIBA 06/2021 - 10/2012
4	Opioid Analgesics (Opioids)IBA 01/2021 - 01/2014
4	AntibodiesIBA 04/2016 - 03/2010
4	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 01/2016 - 03/2011
4	Enterotoxins (Enterotoxin)IBA 05/2010 - 09/2005
3	Anesthetics (Anesthetic Agents)IBA 01/2021 - 10/2012
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 11/2013
3	Saline SolutionIBA 01/2020 - 01/2010
3	CholesterolIBA 11/2018 - 10/2017
3	Laminin ReceptorsIBA 08/2014 - 10/2012
3	DNA (Deoxyribonucleic Acid)IBA 10/2013 - 03/2010
2	Pregabalin (Lyrica)FDA Link 03/2022 - 07/2010
2	ORALIT (ORS)IBA 01/2022 - 09/2015
2	LumicanIBA 01/2022 - 01/2020
2	GraphiteIBA 10/2021 - 01/2020
2	Indicators and Reagents (Reagents)IBA 07/2021 - 01/2019
2	Nefopam (Ajan)IBA 01/2021 - 01/2020
2	CytokinesIBA 01/2021 - 01/2019
2	ImmunosorbentsIBA 01/2021 - 10/2013
2	Transfer RNA (tRNA)IBA 01/2021 - 05/2019
2	RNA (Ribonucleic Acid)IBA 12/2020 - 01/2016
2	Vincristine (Oncovin)FDA LinkGeneric 01/2020 - 11/2012
2	Dextran SulfateIBA 01/2020 - 01/2018
2	Methionine-tRNA LigaseIBA 09/2018 - 12/2011
2	LipidsIBA 10/2017 - 12/2016
2	N 30IBA 09/2017 - 05/2015
2	Insulin (Novolin)FDA Link 04/2016 - 01/2016
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 12/2007
2	Laminin (Merosin)IBA 08/2014 - 01/2014
2	NF-kappa B (NF-kB)IBA 05/2010 - 09/2006
2	Clostridium difficile tcdA proteinIBA 02/2009 - 12/2007
2	SB 203580IBA 12/2007 - 09/2005
2	Interleukin-8 (Interleukin 8)IBA 12/2007 - 09/2005
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 12/2007 - 09/2005
2	Messenger RNA (mRNA)IBA 06/2006 - 06/2004
1	Tramadol (K315)FDA LinkGeneric 03/2022
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 03/2022
1	prostaglandin-inositol cyclic phosphateIBA 03/2022
1	Small Leucine-Rich ProteoglycansIBA 01/2022

Therapy/Procedure

5	Length of Stay 01/2021 - 12/2016
4	Anesthesia 01/2021 - 08/2019
3	Epidural Injections 09/2020 - 01/2014
3	Intravenous Administration 01/2017 - 01/2016
2	Epidural Blood Patch 04/2022 - 12/2018
2	Ligation 03/2022 - 06/2006
2	Critical Care (Surgical Intensive Care) 12/2021 - 07/2021
2	Quantum Dots (Quantum Dot) 10/2021 - 01/2020
2	Therapeutics 01/2020 - 01/2019
2	Drug Therapy (Chemotherapy) 01/2020 - 11/2012
2	Pulsed Radiofrequency Treatment 01/2017 - 05/2009
2	Aftercare (After-Treatment) 01/2014 - 11/2013
2	Vitrectomy 04/2013 - 12/2012
2	General Anesthesia 01/2010 - 09/2009
1	Conservative Treatment 04/2022
1	Radiofrequency Ablation 01/2022
1	Mechanical Ventilators (Ventilator) 12/2021
1	Artificial Respiration (Mechanical Ventilation) 12/2021